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Airways Resistance
In this lab learners use a guinea pig trachea dissection to simulate asthma, and measure the effects of histamine and acetylcholine on airway contraction. Students also observe the effects of drugs used to treat asthma, such as salbutamol and theophylline, and their interaction.
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Chick Biventer Cervicis
在这个实验中,李尔王ners use the isolated biventer cervicis muscle from a chick to investigate how the curare poison affects muscle contraction, and which drugs may work as an antidote to curare.
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Mammalian Atria
在这个实验中,李尔王ners use a guinea pig atria to examine how isoprenaline, propranolol, acetylcholine, atropine, and physostigmine affect the frequency and strength of myocardial contraction.
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Mammalian Diaphragm
在这个实验中,李尔王ners use an isolated phrenic-innervated diaphragm muscle preparation to investigate how suxamethonium, tubocurarine, and edrophonium affect neuromuscular transmission.
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Mammalian Heart
在这个实验中,李尔王ners use an isolated rabbit heart to investigate the effects of epinephrine, norepinephrine, isoproterenol, isoprenaline, acetylcholine, lidocaine, ouabain and a low potassium solution on heart rate and the force of contraction.
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Mammalian Jejunum
在这个实验中,李尔王ners will apply repetitive electrical stimulation to the sympathetic nerves of the isolated rabbit jejunum. This electrical stimulation inhibits rhythmic output from the enteric nerve plexuses, which in turn leads to relaxation of the intestine and reduced gastrointestinal motility. They will also investigate how the drug guanethidine prevents the release of norepinephrine from sympathetic ("adrenergic") nerve terminals.
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Mammalian Uterus
在这个实验中,李尔王ners will examine the effects of oxytocin and epinephrine on an isolated uterus, investigating the effects of a high potassium solution and both beta-adrenergic agonists and antagonists on uterine smooth muscle (myometrium).
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Stimulated Ileum
在这个实验中,李尔王ners will use a guinea pig ileum preparation to investigate how codeine, naloxone, naltrexone, norepinephrine, and acetylcholine affect gastrointestinal motility.
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Stimulated Rat Vas Deferens
在这个实验中,李尔王ners use a stimulated rat vas deferens to study drugs that act presynaptically and test the effects of these drugs on synaptic transmission. They also investigate the effects of a range of adrenoceptor agonists and antagonists.
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Toad Rectus Abdominis
在这个实验中,李尔王ners use an isolated toad rectus abdominis muscle to investigate the effects of tubocurarine and suxamethonium on muscle contraction stimulated by acetylcholine application.
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Unstimulated Ileum
在这个实验中,李尔王ners examine the effects of a variety of drugs on the unstimulated guinea pig ileum preparation. Students also examine the effects of two mystery drugs and determine their mechanism of action.
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Unstimulated Rat Vas Deferens
在这个实验中,李尔王ners use an isolated rat vas deferens to investigate the effects of alpha adrenergic receptor agonists and antagonists, and drugs that affect the amount of norepinephrine in the synaptic cleft.
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Vascular Resistance
在这个实验中,李尔王ners perfuse the isolated hindquarters of a rat at a constant flow. From the changes in pressure required to maintain this flow, the vascular resistance is recorded. While many drugs have an effect on blood pressure, this can be due to a primary effect on the heart (changing flow) or on the vascular bed (changing resistance). To clearly define the site of action in the cardiovascular system, it is often necessary to use a simplified preparation such as the rat hindquarters.
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Vascular Smooth Muscle
In this lab learners will use arterial rings from a pig coronary artery to explore some drug effects. Arterial rings can be used to demonstrate classical responses to autonomic drugs on vascular smooth muscle. Arterial rings can also be used to show the recently-discovered role of the endothelium in modulating vascular responses.
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Lt LabStation超过150已完全可定制的pharmacology, neuroscience and physiology lab lessons.
Educators can create interactive lessons for students to work through in the lab.
Students can record and analyze physiological signals using PowerLab and Lt LabStation to reinforce theory through experimentation.
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